The Ducks fought valiantly against the Pilots, but eventually fell 4-3 on Friday at the Student Tennis Center.
Oregon will put its four-match win streak on the line at 2 p.m. on Friday when the Ducks entertain in-state rival Portland.
Oregon swept its first dual match in over year with the 7-0 win over Santa Clara on Saturday to record its fourth-straight victory.
Nicole Long clinched the match for Oregon against UCSB, 5-2, on the road with her third-straight dual match win.
Oregon will get tested once again on the road, this time in Santa Barbara with a two-match win streak on the line.
Oregon won its second-straight match at home on Sunday with a gritty, 4-3, win over Iowa.
Nia Rose clinched the match for Oregon on Friday at the outdoor tennis courts as UO defeated Montana 5-2.
The Oregon women's tennis team is set to entertain a pair of Midwest teams to wrap up its homestand this weekend.
The Sooners came away with a 6-1 victory over the Ducks Sunday afternoon at the Student Tennis Center.
Oregon looks to bounce back to the win column when they host No. 34 Oklahoma at noon on Sunday, Feb. 8.
The Ducks started the match the way they wanted to, but four-straight singles victories from Minnesota gave the visitors the 4-3 win.
The Oregon women's tennis team will host Minnesota in its home opener at 11 a.m. on Saturday at the Student Tennis Center.